The Effect of Ethyl and Butyl Parabens to Mimic Estrogen to Alter Differentiation of Myeloid Derived Suppressor Cells

Authors

Lyndi Earnshaw, Longwood UniversityFollow
Jessica Savas, Longwood UniversityFollow
Caitlin Harris, Longwood UniversityFollow
Rayven Brown, Longwood UniversityFollow
Annie Choi, Longwood UniveristyFollow

Document Type

Poster

Publication Date

Spring 2019

Abstract

Estrogens have been proven to increase estrogenic activity seen in some cancers. Our research aims to elucidate the effects of xenoestrogens, specifically parabens, on the same oncogenic mechanisms. To compare the effects of ethyl and butyl parabens to natural estrogen, T cell activation and proliferation was measured after exposure to each compound. Understanding the potential effects of parabens as estrogen agonists would allow for safer regulations for use in common food and health products

Comments

Faculty Adviser: Dr. Amorette Barber

Recommended Citation

Earnshaw, Lyndi; Savas, Jessica; Harris, Caitlin; Brown, Rayven; and Choi, Annie, "The Effect of Ethyl and Butyl Parabens to Mimic Estrogen to Alter Differentiation of Myeloid Derived Suppressor Cells" (2019). Spring Showcase for Research and Creative Inquiry. 36.
https://digitalcommons.longwood.edu/rci_spring/36