Document Type
Article
Publication Date
Spring 2018
Abstract
T cells immunity is linked to a complex system of cytokines that determine differentiation of naïve T cells into Th1, Th2, Th17, and Treg cells. Estrogen production or periods of elevated production have been correlated with an anti-inflammatory state in which Th2 and Treg cells are up-regulated. Such responses in the immune system are capable of supporting pre-cancerous activity. We are investigating the tie between the xenoestrogen compounds found in cosmetics, parabens, and their ability to regulate T cell immunity. Testing parabens and paraben derivatives with weaker estrogen receptor association will allow for a better understanding of the interplay between estrogen receptor activation and T cell Immunity.
Recommended Citation
Kintz, Hailey, "Do Paraben Derivatives Alter T Cell Immunity?" (2018). Spring Presentation of Undergraduate Research. 13.
https://digitalcommons.longwood.edu/spur/13
Included in
Biology Commons, Cancer Biology Commons, Immunity Commons, Medicinal and Pharmaceutical Chemistry Commons, Organic Chemicals Commons, Organic Chemistry Commons, Other Chemicals and Drugs Commons, Other Immunology and Infectious Disease Commons, Pharmaceutical Preparations Commons
Comments
Faculty Advisors: Amorette R. Barber and Andrew A. Yeagley