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Perspectives on Research in Science and Mathematics (PRISM)

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Our lab is interested in various medicinal chemistry projects that intersect chemistry and biology. The biological focus of our lab is primarily that of anti-bacterial treatments. More particularly, I am interested in compounds that may be alternative treatments to traditional antibiotics.

One alternative treatment that my post-doctoral lab focused on was the inhibition of bacterial biofilms. Over 80% of bacterial infections in the body are caused not by the presence of bacteria, since they are most often present constantly, but when bacteria manage to form biofilms. It is this biofilm that often provides the bacteria some safety from external pressures (such as antibiotics, our immune system, temperature, pH changes, etc.). The ability to prevent or even disperse the presence of bacterial biofilms presents an interesting alternative treatment that is less susceptible to bacterial resistance.

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Investing aliphatic phosphazenes as quaternary ammonium cation (QACs) mimics

Our lab is interested in various medicinal chemistry projects that intersect chemistry and biology. The biological focus of our lab is primarily that of anti-bacterial treatments. More particularly, I am interested in compounds that may be alternative treatments to traditional antibiotics.

One alternative treatment that my post-doctoral lab focused on was the inhibition of bacterial biofilms. Over 80% of bacterial infections in the body are caused not by the presence of bacteria, since they are most often present constantly, but when bacteria manage to form biofilms. It is this biofilm that often provides the bacteria some safety from external pressures (such as antibiotics, our immune system, temperature, pH changes, etc.). The ability to prevent or even disperse the presence of bacterial biofilms presents an interesting alternative treatment that is less susceptible to bacterial resistance.